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What to Expect After Taking Spravato

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What to Expect After Taking Spravato

For individuals struggling with treatment-resistant depression, finding a solution can feel like an uphill battle. Spravato, a nasal spray form of esketamine, is a breakthrough for treating depression. It works differently than traditional antidepressants and has proven to improve symptoms rapidly.

Horizons Wellness Family Health NP PLLC in Middletown, New York, is a certified Spravato treatment center that provides patients with safe and supervised administration in a compassionate, supportive environment. If you’re considering Spravato or have already started treatment, here’s what you can expect.

The immediate effects after taking Spravato

Unlike traditional antidepressants that take weeks to start working, Spravato works quickly, often within hours or days. Since it affects brain chemistry differently, patients may experience immediate but temporary sensations right after administration.

Common effects within the first few hours

After taking Spravato, some patients report feeling:

  • Mild dizziness or drowsiness
  • A sense of dissociation or detachment from reality
  • Temporary changes in perception
  • A floating or lightheaded sensation

These effects are typical and usually fade within a few hours. Because of these temporary changes, patients must remain at the clinic for monitoring and should arrange for a ride home after each session.

How Spravato impacts mood over time

A significant advantage of Spravato over traditional antidepressants is its ability to rapidly improve symptoms. So often, by the time patients seek help for depression, they’ve been struggling for a while. 

Having to wait up to 12 weeks for traditional antidepressants to work can feel like a lifetime. With Spravato, patients typically begin noticing a difference in mood, energy levels, and overall outlook after just a few sessions.

During the first few weeks of treatment, a patient takes Spravato twice a week, giving the brain time to adjust and respond to the medication. Over time, treatment frequency may decrease as symptoms improve and stability is maintained.

Patients often describe experiencing:

  • A noticeable lift in mood and motivation
  • Reduced feelings of hopelessness and sadness
  • Better emotional balance and resilience

The effects of Spravato build over time, and consistent follow-up with a provider ensures the best long-term results.

Managing side effects and adjusting to treatment

While most side effects are mild and temporary, some patients may experience nausea, headaches, or increased blood pressure during or after treatment. The Horizons Wellness Family Health NP PLLC team closely monitors patients during each session. Patient safety and comfort is our top priority. 

Drinking plenty of water, resting after treatment, and avoiding alcohol or sedatives can help minimize discomfort. Patients who experience persistent side effects should discuss them with our team to explore possible adjustments.

A path to depression relief

If conventional antidepressant medications haven’t adequately controlled your symptoms, or if you’re experiencing significant side effects, consider seeing if Spravato is right for you. Depression shouldn’t dictate the way you live your life. 

Horizons Wellness Family Health NP PLLC provides personalized mental health care to help patients rediscover joy and happiness. If you’re ready to explore Spravato as a treatment option, contact us to schedule a consultation today to learn how it can help you move forward.